- Author:
Yoshiharu KAWAGUCHI
1
;
Shoji SEKI
;
Taketoshi YASUDA
;
Yumiko NAKAMURA
;
Masato NAKANO
;
Tomoatsu KIMURA
Author Information
- Publication Type:Case Report
- Keywords: CSF leakage; Postoperative meningitis; Surgical site infection; Methicillin-resistant Staphylococcus epidermidis; Linezolid
- MeSH: Acetamides; Debridement; Humans; Japan; Meningitis; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcus; Sutures; Linezolid
- From:Asian Spine Journal 2010;4(2):136-140
- CountryRepublic of Korea
- Language:English
- Abstract: Postoperative meningitis after spinal surgery is a rare complication that can result in a life-threatening condition. Linezolid (LZD) is an oxazolidinone which has been approved in Japan for infections caused by methicillin-resistant Staphylococcus aureus. The authors encountered a case of postoperative meningitis with cerebrospinal fluid leakage (liquorrhoea) that occurred after resection of a cervical cord tumor. The infection was caused by methicillin-resistant Staphylococcus epidermidis(MRSE). Debridement and suture of the dura matter was carried out. LZD was given intravenously. The infection was cured without any sequelae. Based on this result, we concluded that LZD might be considered as one of the first choices for the treatment of postsurgical meningitis caused by MRSE.