The prevalence of hypertension and its associated factors in patients with rheumatoid arthritis
10.3760/cma.j.cn141217-20210129-00045
- VernacularTitle:类风湿关节炎患者高血压患病率及相关因素分析
- Author:
Yaowei ZOU
1
;
Jianzi LIN
;
Chutao CHEN
;
Jianda MA
;
Lefeng CHEN
;
Tao WU
;
Xuepei ZHANG
;
Yaoyao ZOU
;
Donghui ZHENG
;
Lie DAI
Author Information
1. 中山大学孙逸仙纪念医院风湿免疫科，广州 510120
- Keywords:
Arthritis, rheumatoid;
Hypertension;
Cardiovascular disease;
Comorbidity
- From:
Chinese Journal of Rheumatology
2022;26(3):152-159
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the prevalence of hypertension and its associated factors in rheumatoid arthritis (RA) patients.Methods:Consecutive Chinese patients with RA were recruited from August 2015 to September 2019 at Department of Rheumatology, Sun Yat-sen Memorial Hospital. Demo-graphic data and clinical data were collected including indicators of disease activity, functional assessment and radiographic assessment, comorbidities and previous medications. Logistic regression analysis was used to evaluate the related factors of hypertension in RA patients.Results:There were 674 RA patients recruited with 82.3%(555/674) female and mean age (50±13) years. The prevalence rate of hypertension was 32.9% (222/674), followed by dyslipidemia (9.9%, n=67), type 2 diabetes (8.8%, n=59), hyperuricemia (8.5%, n=43), fatty liver disease (8.0%, n=54), cardiovascular disease (6.2%, n=42) and chronic kidney disease (3.3%, n=22). Compared with those without hypertension, RA patients with hypertension had advanced age with longstanding disease duration, higher disease activity indicators, worse joint destruction, and higher proportions of comorbidities. Multivariate logistic regression analysis showed that comorbidities including hyperuricemia [ OR=1.977, 95% CI(1.002, 3.900)], dyslipidemia [ OR=1.903, 95% CI(1.102, 3.288)] and fatty liver disease [ OR=2.335, 95% CI(1.278, 4.265)] were risk factors of hypertension after adjustment for age and gender. Conclusion:Hyperten-sion is the most common comorbidity in RA patients which is associated with comor-bidities including hyperuricemia, dyslipidemia and fatty liver disease. Detection and management of hyperten-sion and other cardiovascular disease related comorbidities in RA patients should be emphasized.
