Application of three-dimensional shear wave elastography in the differential diagnosis of benign and malignant breast masses
10.3760/cma.j.cn131148-20210804-00529
- VernacularTitle:三维剪切波弹性成像鉴别诊断乳腺良恶性结节的应用价值
- Author:
Jianqiao XUE
1
;
Xujie WANG
;
Xiaoli ZHAN
;
Jinjin LIU
;
Yan ZHENG
;
Fenglin DONG
Author Information
1. 苏州大学附属第一医院超声科，苏州 215006
- Keywords:
Ultrasonography;
Shear wave elastography;
Breast diseases;
Stiff rim sign
- From:
Chinese Journal of Ultrasonography
2022;31(5):427-432
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the application value of three-dimensional shear wave elastography(3D-SWE) with quantitative parameters and qualitative analysis of stiff rim sign in differentiating benign and malignant breast masses.Methods:One hundred and seventeen female patients (121 breast masses) admitted to the First Affiliated Hospital of Soochow University from January 2020 to February 2021 were examined by conventional ultrasound, two-dimensional shear wave elastography (2D-SWE) and 3D-SWE. Surgical or puncture pathology were used as the gold standard, the ROC curves of 2D-SWE and 3D-SWE were drawn to obtain the optimal qualitative and quantitative indicators. Afterwards, BI-RADS category was adjusted according to the optimal indicators, which could be used to evaluate the diagnostic value in differentiating benign and malignant breast masses.Results:The area under ROC curve (AUC) of BI-RADS category was 0.846, the sensitivity and specificity were 89.6% and 79.6%, respectively. The AUC value of mass-to-fat elasticity ratio(Eratio) of coronal plane was 0.869, which was the highest among all quantitative parameters and was significantly higher than that of 2D-SWE ( P<0.05). In addition, the AUC value of stiff rim sign of coronal plane was significantly higher than those of 2D-SWE, sagittal plane and transverse plane (All P<0.05). The AUC of combination of stiff rim sign of coronal plane and conventional US was 0.901, which was significantly higher than that using conventional ultrasound alone( P<0.05). Conclusions:Compared with 2D-SWE, Eratio and stiff rim sign of coronal plane of 3D-SWE yield better diagnostic efficiency.Adjusting stiff rim sign coronal plane to BI-RADS category can effectively improve the diagnostic efficiency.
