Application of pressure-strain loops in evaluating early left ventricular myocardial work in patients with metabolic syndrome
10.3760/cma.j.cn131148-20211011-00721
- VernacularTitle:压力-应变环评估代谢综合征患者早期左室心肌做功
- Author:
Lijuan SUN
1
;
Chengwei XIAO
;
Xiaoxue CHEN
;
Di WANG
;
Kun XUE
;
Zhengqin QI
Author Information
1. 河北医科大学附属秦皇岛市第一医院 秦皇岛市第一医院超声诊断科，秦皇岛 066000
- Keywords:
Ultrasonography;
Metabolic syndrome;
Myocardial work;
Ventricular function, left
- From:
Chinese Journal of Ultrasonography
2022;31(5):414-419
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate early left ventricular myocardial work in patients with metabolic syndrome (MS) by pressure-strain loops (PSL).Methods:From September 2020 to April 2021, 70 MS patients in the First Hospital of Qinhuangdao Affiliated to Hebei Medical University without left ventricular remodeling were selected as MS group and 65 normal controls as control group, PSL was used to obtain the myocardial power parameters, including global work index (GWI), global work efficiency (GWE), global constructive work (GCW) and global wasted work (GWW). The changes of the parameters were compared between the two groups and their correlations with biochemical parameters were performed in MS group.Results:The left ventricular global longitudinal strain (GLS), GWI, GCW and GWE in MS group were lower than those in normal group, while GWW was higher than that in normal group ( P<0.05). Pearson correlation analysis showed that GWI was positively correlated with high-density lipoprotein cholesterol (HDL-C) ( r=0.194, P<0.05), and negatively correlated with diastolic blood pressure (DBP), waist circumference (WC), fasting blood glucose (Glu), triglyceride (TG) and GLS ( r=-0.257, -0.452, -0.239, -0.193, -0.758, all P<0.05). GWE was negatively correlated with SBP, DBP, WC, Glu, TG and GLS ( r=-0.360, -0.269, -0.326, -0.352, -0.265, -0.663, all P<0.01), and positively correlated with HDL-C ( r=0.201, P<0.05). GCW was negatively correlated with WC and GLS ( r=-0.299, -0.737; all P<0.001). GWW was positively correlated with SBP, DBP, WC, Glu, TG and GLS ( r=0.435, 0.308, 0.413, 0.547, 0.272, 0.400, all P<0.01), and negatively correlated with HDL-C ( r=-0.336, P<0.001). Conclusions:PSL can quantitatively evaluate the changes of early myocardial work in MS patients with good repeatability and has certain clinical value.
