Comparison of left ventricular function in patients with gestational diabetes mellitus prenatal and postpartum by two-dimentional speckle tracking echocardiography
10.3760/cma.j.cn131148-20210907-00635
- VernacularTitle:二维斑点追踪成像对妊娠期糖尿病患者产前及产后左心室功能的对比研究
- Author:
Liping ZHONG
1
;
Jianghua CHEN
;
Guohui YAN
;
Shufen GAN
Author Information
1. 厦门大学附属中山医院超声医学科，厦门 361004
- Keywords:
Echocardiography;
Two-dimensional speckle-tracking imaging;
Gestational diabetes mellitus;
Ventricular function, left
- From:
Chinese Journal of Ultrasonography
2022;31(4):283-288
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the value of routine echocardiography and two-dimensional speckle tracking echocardiography in evaluating the left ventricular function of patients with gestational diabetes mellitus (GDM) prenatal and postpartum.Methods:Twenty-two patients with clinically confirmed GDM in Xiamen Zhongshan Hospital from October 2019 to December 2020 were chosed as the case group, and 22 healthy pregnant women were chosed as the control group. Routine echocardiography and two-dimensional speckle tracking echocardiography were performed in the third trimester and about 3 months postpartum. Routine echocardiographic parameters and longitudinal strain (LS), circumfirential strain (CS) were obtained. The correlation between global longitudinal strain(GLS) and other cardiac function parameters was analyzed. The relationship between clinical parameters of pregnant women and GLS was analyzed by multiple linear regression.Results:In comparison with the control group, the interventricular septal diameter at disatole, left ventricular posterior wall diameter at diastole, Tei index were increased, e′ was decreased in GDM group(all P<0.05); the GLS, each layer LS of GDM group were lower than the control group(all P<0.05), the GLS, each layer LS and torsion parameters were improved at 3 months postpartum(all P<0.05). There was a negative correlation between GLS and Tei( r=-0.224, P=0.036). GLS and HbA 1c was linearly correlated with the regression equation: GLS=-27.458+ 1.534×HbA 1c( R2=0.115). Conclusions:The left heart function of pregnant women with GDM in the third trimester are significantly impaired, but the cardiac function recovers to a certain extent about 3 months after delivery. Two-dimentional speckle-tracking echocardiography is a more accurate and sensitive technique to evaluate the early damage of cardiac function in pregnant women with GDM.
