A Case of Membranoproliferative Glomerulonephritis Type II: Dense Deposit Disease, DDD.
- Author:
Hae Sik KWON
1
;
Seung Jin OH
;
Young Mock LEE
;
Ji Hong KIM
;
Pyung Kil KIM
;
Hae Youn KANG
;
Hyeon Joo JEONG
;
In Joon CHOI
Author Information
1. Department of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine, Seoul, Korea. ped@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Acquired primary glomerular disease;
Dense deposit disease;
Memmbranoproliferative glomerulonephritis;
Proteinuria;
Hematuria;
Acute poststreptococcal glomerulonephritis
- MeSH:
Biopsy;
Child;
Dichlorodiphenyldichloroethane*;
Edema;
Glomerulonephritis, Membranoproliferative*;
Hematuria;
Humans;
Male;
Membranes;
Nephrotic Syndrome;
Proteinuria;
Young Adult
- From:Journal of the Korean Society of Pediatric Nephrology
2001;5(2):188-195
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Type II membranoproliferative glomerulonephritis (Dense deposit disease ) is an acquired primary glomerular disease characterized by electron microscopic evidence of a continuous dense membrane deposition replacing the lamina densa. It is a subtype of idiopathic membra- noproliferative glomrulonephritis, and was described as a separate entity by Berger and Galle in 1963. It frequently occurs in older chilren and young adults and the clinical course is variable, but is generally progressive. The presenting feature is nephrotic syndrome in many patients, and proteinuria and hematuria are also seen frequently. The purpose of this paper is to present a case of DDD (Dense deposit disease) from a 10 year old boy who was diagnosed as a acute poststreptococcal glomurulonephritis with protenuria, hematuria, and facial edema by renal biopsy 4 years ago.