Analysis of risk factors of death after cardiopulmonary bypass in children with congenital heart disease less than 5 kg
10.3760/cma.j.cn101721-20211013-000178
- VernacularTitle:5 kg以下先天性心脏病患儿行体外循环心脏手术后死亡危险因素分析
- Author:
Jingjuan YANG
1
;
Weixun DUAN
;
Yanyan LI
Author Information
1. 空军军医大学第一附属医院心外科,西安 710032
- Keywords:
Congenital heart disease;
Cardiopulmonary bypass;
Low body mass;
Operative death;
Risk factors
- From:
Clinical Medicine of China
2022;38(1):73-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors for surgical death in children with congenital heart disease (CHD) less than 5 kg undergoing cardiopulmonary bypass.Methods:The clinical data of 225 children with CHD who underwent open cardiopulmonary bypass in the First Affiliated Hospital of Air Force Military Medical University from February 2017 to February 2020 were collected for a retrospective case-control study. The independent sample T test was used for inter-group comparison of measurement data, Chi square test or chi squre correction test was used for the comparision between count data. Mann-Whitney rank-sum test was used for rank distribution data and multiple Logistic regression analysis was performed for factors affecting surgical death of children with CHD.Results:Among the 225 cases, 204 (90.67%, 204/225) survived surgery and 21 (9.33%, 21/225) died. Univariate analysis showed that age (2.48±0.68) months and body weight (2.28±0.56) kg in the death group were significantly lower than that in the survival group (4.92±0.65) months ( t=16.33, P<0.001) and body weight (4.26±0.52) kg ( t=16.38, P<0.001), while the proportion of female (66.67% (14/21)), malnutrition (none: 14.28% (3/21); Mild: 42.86% (9/21). Severity: 42.86%(9/21)), palliative surgery proportion (28.57%(6/21)), emergency surgery proportion (71.43%(15/21)), congenital heart surgery risk assessment (RACHS-1) grading ratio (
