Four cases of Stevens-Johnson Syndrome associated with Methazolamide Treatment.
- Author:
Eun Young AHN
1
;
Jee Bum LEE
;
Seung Chul LEE
;
Young Ho WON
Author Information
1. Department of Dermatology, Chonnam University Medical School, Kwangju, Korea.
- Publication Type:Case Report
- Keywords:
Methazolamide;
Stevens-Johnson syndrome;
Korean
- MeSH:
Asian Americans;
Asian Continental Ancestry Group;
Carbonic Anhydrase Inhibitors;
Carbonic Anhydrases;
Glaucoma;
Humans;
Intraocular Pressure;
Methazolamide*;
Stevens-Johnson Syndrome*
- From:Korean Journal of Dermatology
2000;38(6):798-801
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Methazolamide is a carbonic anhydrase inhibitor commonly used for lowering intraocular pressure in glaucoma and other ophthalmologic diseases. Carbonic anhydrase inhibitors are sulfonamide derivatives that are known to cause many adverse side effects, including dermatologic reactions. Recently, Stevens-Johnson syndrome (SJS) associated with methazolamide treatment has been reported in Japanese and Japanese Americans, and it suggested a relationship between genetic background and methazolamide-induced SJS. We report four cases of SJS induced by methazolamide. Methazolamide should be prescribed with caution in patients of Japanese or Korean descent.
