Clinical application of autologous platelet separation in different time courses of cardiovascular surgery
10.3760/cma.j.cn431274-20211126-01237
- VernacularTitle:不同时程心脏大血管手术中自体血小板分离回输的临床应用
- Author:
Yuxin ZENG
1
;
Cong NIE
;
Jiahao PAN
;
Jiawen LUO
;
Ming WU
;
Fei CHEN
;
Daling YI
;
Chunfang TANG
;
Wenwu ZHOU
Author Information
1. 湖南省人民医院（湖南师范大学附属第一医院）心脏大血管外科，长沙 410005
- Keywords:
Cardiac surgical procedures;
Aortic diseases;
Extracorporeal circulation;
Autologous platelet separation
- From:
Journal of Chinese Physician
2022;24(4):577-581
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical significance of autologous platelet separation (APS) in different time courses of cardiovascular surgery.Methods:The relevant data of 75 patients with cardiovascular surgery from September 2019 to August 2021 in Hunan Provincial Peoples′ Hospital were collected retrospectively. They were divided into two groups according to whether APS was used during the operation: group A used APS (37 cases) and group B did not use APS (38 cases). The two groups were divided into subgroups according to the length of cardiopulmonary bypass (CPB): A1 and B1 were medium and short-term groups (CPB bypass time ≤200 min), and A2 and B2 were long-term groups (CPB bypass time >200 min). Blood routine, postoperative drainage volume, postoperative blood product infusion volume and thromboelastogram at different time points were recorded and compared.Results:The postoperative drainage volume, red blood cell infusion volume and ventilator assisted time in group A were less than those in group B (all P<0.05); The postoperative drainage volume [(645.79±205.25)ml vs (886.67±360.96)ml, P=0.006], erythrocyte infusion volume [(3.24±2.53)U vs (4.77±1.97)U, P=0.016], platelet infusion volume [0.00(0.00, 0.00)U vs 1.00(0.125, 2.00)U, P=0.002] and thromboelastogram coagulation reaction time [(7.38±1.74)min vs (9.09±3.57)min, P=0.047] in group A2 were significantly better than those in group B2 (all P<0.05); There were no significant difference in the above indexes between A1 and B1 group (all P>0.05). Conclusions:APS can improve the coagulation function of patients undergoing cardiopulmonary bypass and reduce the amount of bleeding and blood products. Its protective effect is more prominent in high-risk cardiovascular surgery with long cardiopulmonary bypass and complex operation.
