Research progress of Toll-like receptors and pulmonary infection
10.3760/cma.j.cn431274-20210101-00001
- VernacularTitle:Toll样受体与肺部感染的研究进展
- Author:
Yaqi SHENG
1
;
Huadong ZHU
Author Information
1. 中国医学科学院北京协和医学院,北京协和医院急诊科,疑难重症及罕见病国家重点实验室,北京 100730
- Keywords:
Toll-like receptors;
Pneumonia;
Lung diseases, infectious
- From:
Journal of Chinese Physician
2022;24(3):473-476
- CountryChina
- Language:Chinese
-
Abstract:
Due to the increase of susceptible individual species and drug-resistant pathogens, pulmonary infection is still a global problem that threatens human health. Toll-like receptors (TLR) can identify pathogenic pattern related molecules on the surface of pathogenic microorganisms in innate immunity and initiate innate immune response. It can participate in different anti-infection mechanisms and play an important role in pulmonary infectious diseases caused by different pathogens. In this paper, the research progress of TLR in pulmonary infection at home and abroad in recent years is reviewed.