Primary mediastinal giant malignant synovial sarcoma: two cases reports
10.3760/cma.j.cn431274-20210217-00196
- VernacularTitle:原发性纵隔巨大恶性滑膜肉瘤2例报告
- Author:
Wenpeng HUANG
1
;
Rongming ZHANG
;
Liming LI
;
Zhigang ZHOU
;
Jianbo GAO
Author Information
1. 郑州大学第一附属医院放射科，郑州 450052
- Keywords:
Sarcoma, synovial;
Mediastinal neoplasms;
Tomography, X-ray computed;
Diagnostic imaging
- From:
Journal of Chinese Physician
2022;24(3):346-349
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the clinical features and computed tomography (CT) imaging performance of mediastinal giant malignant synovial sarcoma (SS) and to improve the clinicians′ diagnosis and treatment of this disease.Methods:We report the clinical data of 2 cases of primary mediastinal giant malignant SS, and reviews the literature for CT presentation and differential diagnosis.Results:Primary giant malignant SS of mediastinum is rare in clinic. CT showed irregular cystic and solid mass with mural nodules, adjacent osteolytic destruction, unclear boundary with adjacent tissues. The enhancement showed that the solid components of the tumor and mural nodules were enhanced, while the cystic necrosis area had no enhanced uneven enhancement. The two cases in this paper showed " borehole-like" growth above the clavicle and growth into the left thoracic cavity, with pulmonary metastasis and lymphatic metastasis respectively.Conclusions:Mediastinal malignant SS is a rare disease with high malignancy and easy to metastasize, which emphasizes " early detection, early diagnosis and early treatment" . It should be taken into account in the differential diagnosis of mediastinal tumors, but the confirmation of diagnosis needs to be combined with pathological and immunohistochemical findings. Clinicians need to take advantage of imaging examinations to provide auxiliary guidance on the diagnosis, metastasis assessment and surgical treatment options of SS.
