Therapeutic effect of enteral nutrition support in the transformation therapy of advanced gastric cancer
10.3760/cma.j.cn431274-20220301-00149
- VernacularTitle:肠内营养支持治疗在晚期胃癌转化治疗中的疗效观察
- Author:
Fang WU
1
;
Wenfa LIN
;
Xufan CAI
;
Zhenyuan QIAN
;
Zaiyuan YE
Author Information
1. 浙江省人民医院（杭州医学院附属人民医院）普通外科胃肠胰外科，杭州 310014
- Keywords:
Stomach neoplasms;
Enteral nutrition;
Transformation therapy
- From:
Journal of Chinese Physician
2022;24(3):326-329
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of enteral nutrition support in the transformation therapy of advanced gastric cancer.Methods:Eighty-two patients with advanced gastric cancer treated by transformation in Zhejiang Provincial People′s Hospital from September 2019 to August 2021 were analyzed retrospectively. 41 patients in the observation group were treated with enteral nutrition support on the basis of routine transformation treatment; 41 patients in the control group received only routine transformation treatment. The nutritional related indexes such as prealbumin, total serum protein and albumin and immune related indexes such as CD4 + , CD8 + , CD4 + /CD8 + were detected before treatment and on the 7th day after the end of 3-cycle transformation treatment, and the above indexes and transformation success rate of the two groups were compared. Results:There was no significant difference in prealbumin, total serum protein, albumin, CD4 + , CD8 + , CD4 + /CD8 + between the two groups before treatment (all P>0.05). On the 7th day after three cycles of transformation treatment, the above indexes in the observation group were higher than those in the control group, with significant difference (all P<0.05). The success rate of transformation in the observation group was higher than that in the control group ( P<0.05). Conclusions:The rational use of enteral nutrition support in the transformation treatment of patients with advanced gastric cancer can significantly improve the nutritional status and immune function of patients, increase the tolerance to chemotherapy and improve the success rate of transformation.
