Clinical progress of monogenic autoimmune syndrome associated with type 1 diabetes mellitus
10.3760/cma.j.cn431274-20211211-01298
- VernacularTitle:1型糖尿病相关单基因自身免疫性综合征临床进展
- Author:
Huifang PENG
1
;
Qianwen DUAN
;
Yujin MA
;
Liujun FU
;
Hongwei JIANG
Author Information
1. 河南科技大学临床医学院，河南科技大学第一附属医院内分泌代谢中心，河南省遗传罕见病医学重点实验室，国家代谢性疾病临床医学研究中心-分中心，洛阳 471003
- Keywords:
Diabetes mellitus, type 1;
Autoimmune syndrome;
Monogenic disease
- From:
Journal of Chinese Physician
2022;24(2):196-200
- CountryChina
- Language:Chinese
-
Abstract:
The impairment of islets β cell by autoimmune response is an important cause of type 1 diabetes mellitus (T1DM). Some monogenic autoimmune syndromes could induce T1DM in difference chance, which are important disease models to deeply understand autoimmunity and T1DM. This article reviews the diagnosis, treatment and genetic detection of eight known single gene autoimmune syndromes associated with T1DM, arming to expand the diagnosis and treatment of T1DM.
