Clinical characteristics of lung cancer associated acute ischemic stroke and atrial fibrillation associated acute ischemic stroke
10.3760/cma.j.cn431274-20200921-01303
- VernacularTitle:肺癌相关急性缺血性脑卒中与心房纤颤相关急性缺血性脑卒中临床特点
- Author:
Siting WU
1
;
Jiacai LIN
;
Hui LIU
;
Fang CUI
;
Rui XU
Author Information
1. 中国人民解放军总医院海南医院神经内科，三亚 572013
- Keywords:
Lung neoplasms;
Atrial fibrillation;
Acute ischemic stroke
- From:
Journal of Chinese Physician
2022;24(1):49-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical characteristics of lung cancer associated acute ischemic stroke (LCA-AIS) and atrial fibrillation associated acute ischemic stroke (AFA-AIS).Methods:From January 1, 2014 to December 31, 2018, 46 patients diagnosed with LCA-AIS (LCA-AIS group)in Hainan Hospital of Chinese PLA General Hospital were selected, and 46 patients diagnosed with AFA-AIS (AFA-AIS group) were matched according to age and sex.The general situation, laboratory test results and imaging results of the two groups were analyzed.Results:(1) The neurological deficit symptoms in AFA-AIS group were more serious than those in LCA-AIS group; there was significant difference in National Institutes of Health Stroke Scale (NIHSS) score and the Modified Rankin Scale (mRs) score between the two groups ( P=0.001, P=0.003). (2)The D-D polymer concentration in LCA-AIS group was significantly higher than that in AFA-AIS group ( P<0.001), but the hemoglobin, erythrocyte count and hematocrit were significantly lower than those in AFA-AIS group (all P<0.001). (3)There was no significant difference in imaging classification and the number of infarct basins between LCA-AIS group and AFA-AIS group ( P>0.05). LCA-AIS patients was more likely to have poly-period acute ischemic lesions ( P=0.015), while AFA-AIS had significantly larger infarct diameter and more likely to be complicated with acute hemorrhagic stroke or bleeding ( P<0.001). Conclusions:The clinical characteristics of LCA-AIS and AFA-AIS are similar, so it is necessary to distinguish LCA-AIS from AFA-AIS in combination with neurological impairment, laboratory tests and imaging findings to avoid misdiagnosis.
