Effect of intensity-modulated radiotherapy guided by CT/MRI image fusion technology in patients with nasopharyngeal carcinoma
10.3760/cma.j.cn431274-20200810-01104
- VernacularTitle:CT/MRI图像融合技术下调强放疗在鼻咽癌患者中的应用效果
- Author:
Juanjuan ZHAO
1
;
Chengjun GENG
Author Information
1. 江苏省无锡市九〇四医院放射科 214044
- Keywords:
Nasopharyngeal neoplasms;
Radiotherapy, intensity-modulated;
Image processing, computer-assisted;
Tomography;
Magnetic resonance imaging
- From:
Journal of Chinese Physician
2021;23(12):1842-1846
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the application effect of intensity-modulated radiotherapy guided by computed tomography/magnetic resonance imaging (CT/MRI) fusion technology in patients with nasopharyngeal carcinoma.Methods:The case data of 112 patients with nasopharyngeal carcinoma in 904 Hospital from June 2013 to January 2018 were retrospectively analyzed. They were divided into control group (three-dimensional conformal radiotherapy guided by CT/MRI image fusion technology) and observation group (intensity-modulated radiotherapy guided by CT/MRI image fusion technology), with 56 cases in each group. The average target volume, short-term efficacy, incidence of toxic and side effects of radiotherapy, 1, 2 and 3-year survival rate and recurrence rate were compared between the two groups.Results:The target volume in the observation group was larger than that in the control group ( P<0.05), and the total effective rate (78.57%) was higher than that in the control group (60.71%, P<0.05); There was no significant difference in the incidence of dry mouth, temporomandibular joint injury, hearing loss and skin injury between the two groups ( P>0.05), but there was significant difference in the total incidence of toxic and side effects ( P<0.05); There was no significant difference in 1-year and 2-year survival rate and recurrence rate between the two groups ( P>0.05); The 3-year survival rate (82.14%) in the observation group was higher than that in the control group (64.29%), and the recurrence rate (8.93%) was lower than that in the control group (23.21%, P<0.05). Conclusions:CT/MRI image fusion technology can guide the intensity-modulated radiotherapy in patients with nasopharyngeal carcinoma, which can improve the accuracy of radiotherapy target volume delineation and the total effective rate of treatment and 3-year survival rate, and reduce the 3-year recurrence rate. It is worthy of clinical promotion and application.
