A 5-year epidemiological follow-up study on hyperparathyroxinemia in Urumqi community residents
10.3760/cma.j.cn431274-20210402-00382
- VernacularTitle:乌鲁木齐社区居民高甲状旁腺素血症的5年流行病学随访研究
- Author:
Maimaiti NURONGGULI
1
;
Kaidi ZHANG
;
Shuqing XING
;
Yan HENG
;
Hui LI
;
Atawula MUNIRE
;
Xinling WANG
;
Yanying GUO
Author Information
1. 新疆维吾尔自治区人民医院内分泌科，乌鲁木齐 830001
- Keywords:
Parathyroid hormone;
Vitamin D;
Epidemiologic methods;
Follow-up studies
- From:
Journal of Chinese Physician
2021;23(12):1810-1813
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Based on the previous epidemiological investigation of hyperparathyroxinemia in Urumqi community, a follow-up study was conducted to understand the changes of serum parathyroid hormone (PTH) level and clinical characteristics of residents with PTH.Methods:In the previous study (2013), an epidemiological cross-sectional study of hyperparathyroxinemia was conducted on 1 473 residents of the resident community, and 180 people with hyperparathyroxinemia were found. The serum PTH, parathyroid related laboratory indexes and vitamin D were observed in high PTH population of different genders.Results:According to the inclusion criteria, 159 patients with high PTH were included in the study. The total follow-up rate was 88.3% (159/180), including 24 males (15.09%) and 135 females (84.91%). The serum PTH level in the follow-up population was 68.60 (47.85-98.80)pg/ml, which was significantly different from that in the first visit ( P<0.01). There was no significant difference in serum PTH levels between men and women ( P>0.05). The levels of serum 25(OH)D, calcium, phosphorus, magnesium, creatinine, albumin and alkaline phosphatase in the follow-up population had no significant changes compared with the first visit population (all P>0.05); After stratified by sex, the serum creatinine level of men with high PTH was significantly higher than that of women ( P<0.01), and there was no significant difference in other PTH related laboratory indexes ( P>0.05); Although the vitamin D level was still deficient (<20 ng/ml), the proportion of people with sufficient vitamin D was significantly higher than that at the first visit. Conclusions:25(OH) D deficiency was still common in the follow-up population, but the vitamin D level of the residents with PTH was significantly improved and the serum PTH level was significantly lower than that in the first visit.
