The relationship between insomnia and cognitive impairment in adolescents: chain mediating effects of fatigue, depression and anxiety
10.3760/cma.j.cn371468-20210928-00559
- VernacularTitle:疲乏和抑郁焦虑情绪在青少年失眠与认知缺陷之间的链式中介作用
- Author:
Lingfei CHENG
1
;
Leilei WANG
;
Tingting WANG
;
Shuangjiang ZHOU
;
Jinmeng LIU
;
Jingxu CHEN
Author Information
1. 北京回龙观医院睡眠医学中心，北京 100096
- Keywords:
Adolescent;
Insomnia;
Cognitive impairment;
Fatigue;
Depression;
Anxiety
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2022;31(4):346-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the situation of insomnia, fatigue, depression, anxiety and cognitive impairment in adolescents with different characteristics, and the chain mediating effect of fatigue, depression and anxiety on insomnia and cognitive impairment.Methods:The general demographic data of 6 014 adolescents were collected.Insomnia severity index (ISI), the multidimensional fatigue inventory (MFI-20), patient health questionnaire-9 (PHQ-9), generalized anxiety disorder-7 (GAD-7) and perceived deficits questionnaire-depression(PDQ-D) were used to compare the insomnia, fatigue, depression, anxiety and cognitive impairment of adolescents with different characteristics.Spearman correlation analysis was conducted by SPSS 20.0 software.The significance of mediating effect was tested by deviation corrected nonparametric percentile Bootstrap method using SPSS macro program PROCESS.Results:The detection rates of insomnia, fatigue, depression, anxiety and cognitive impairment were different in adolescents with different genders, grades and academic achievements.Cognitive impairment was significantly positively correlated with insomnia ( r=0.654, P<0.01), fatigue ( r=0.476, P<0.01), depression ( r=0.677, P<0.01), anxiety ( r=0.655, P<0.01), which was suitable for mediating effect test.Fatigue, depression and anxiety in adolescents had a chain mediating effect between insomnia and cognitive impairment.Insomnia indirectly affects cognition by affecting fatigue and depressive symptoms.The intermediary effect value was 1.253, the effect amount was 55.60%, and the total effect was 2.254.Insomnia indirectly affects cognition by affecting fatigue and anxiety symptoms.The intermediary effect value was 1.161, the effect amount was 51.50%, and the total effect was 2.254. Conclusion:Insomnia can not only directly affect their cognitive impairment, but also indirectly affect their cognitive impairment through the chain mediation of fatigue, depression and anxiety of adolescents.
