International clinical research of critical care medicine in 2021
10.3760/cma.j.cn121430-20211220-01889
- VernacularTitle:2021国际重症医学临床研究进展
- Author:
Qingdong LI
1
;
Ziqi RONG
;
Pengyu LU
;
Wei HUANG
Author Information
1. 大连医科大学附属第一医院疾病预防与院内感染控制部，辽宁大连 116012
- Keywords:
Critical care medicine;
Sepsis;
Septic shock;
Acute respiratory distress syndrome;
Guideline;
Therapy
- From:
Chinese Critical Care Medicine
2022;34(1):5-11
- CountryChina
- Language:Chinese
-
Abstract:
The progress of critical care medicine in 2021 is still encouraging. The new international guideline for management of sepsis and septic shock came out after 4 years. Besides, a couple of preferable clinical evidences were released including restrictive blood transfusion strategy for patients with acute myocardial infarction, prevention of peripheral venous catheter infection, heparin inhalation and driving pressure setting in patients with acute respiratory distress syndrome (ARDS), lower oxygenation target for acute hypoxemic respiratory failure, low level positive end-expiratory pressure in non-ARDS patients with respiratory failure, light sedation or non-sedation strategy, biological phenotypes, as well machine learning in sepsis and ARDS. However, we also encounter negative results such as balanced solution during fluid resuscitation, hypothermia therapy after out-of-hospital cardiac arrest or traumatic brain injury, adrenomedullin-specific antibody adrecizumab therapy and coupled plasma filtration-adsorption (CPFA) therapy for patients with septic shock, extracorporeal carbon dioxide removal (ECCO 2R) implementation in acute hypoxic respiratory failure, continuous infusion of hypertonic saline in patients with traumatic brain injury. Collectively, in the future, individualized diagnosis and management based on the principle of "wise choice" will become the daily practice scene for all intensivists.
