Effect of fermented soybean curd residue (FSCR; SCR-meju) by aspergillus oryzae on the anti-obesity and lipids improvement.
10.4163/jnh.2013.46.6.493
- Author:
Sang Il LEE
1
;
Ye Kyung LEE
;
Soon Dong KIM
;
Ji Ean LEE
;
Jongkeun CHOI
;
Jong Phil BAK
;
Jong Hwan LIM
;
Joo Won SUH
;
In Ae LEE
Author Information
1. Department of Food, Nutrition and Culinary Arts, Keimyung College, Daegu 704-703, Korea.
- Publication Type:Original Article
- Keywords:
soybean curd residue (SCR, biji);
aspergillus oryzae;
SCR-meju (biji-meju);
anit-obesity;
antioxidant enzymes
- MeSH:
Animals;
Aspergillus oryzae*;
Aspergillus*;
Body Weight;
Diet;
Diet, High-Fat;
Hyperlipidemias;
Hypertension;
Liver Diseases;
Mice;
Mice, Obese;
Obesity;
Oryza;
Soybeans*
- From:Journal of Nutrition and Health
2013;46(6):493-502
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In this study, we designed to confirm the dietary effect of anti-obesity of fermented soybean curd residue (FSCR; SCR-Meju; Biji-meju) by A. oryzae, which is well known as a Korean traditional meju microbe. We observed that body weight gain, serum and hepatic lipid profile, as well as the activity of ROS generating enzyme and ROS scavenging enzyme in high-fat diet induced obese mice fed experimental diet (SCR and SCR-meju). Body weight gain and epididymal fat weight of HC (high-fat diet control) was markedly higher than that of NC (Normal control). Conversely, body weight gain and epididymal fat weight of the SCR (Biji) and SCR-meju (Biji-meju) group was significantly lower than that of HC; these of the SCR-meju group was lower than that of the SCR group. Furthermore, serum TG and total-cholesterol and LDL-cholesterol contents of SCR and SCR-meju groups were lower than that of HC, and HDL-cholesterol level of the SCR-meju group was significantly higher than that of HC. In conclusion, although precise mechanisms of the antiobese effects of SCR-meju in this study are unknown, the present study provides an experimental evidence that SCR-meju may prevent obesity and obesity related metabolic syndromes, such as hyperlipidemia, hypertension and diabetes, and liver disease by high-fat diet. Nevertheless, further study in this filed will be needed.
