Value of modified early warning score combined with D-dimer test for establishment of an acute pancreatitis severity evaluation model
10.3760/cma.j.issn.1008-6706.2022.05.002
- VernacularTitle:改良早期预警评分联合D-二聚体检查用于急性胰腺炎严重程度评估模型建立的价值
- Author:
Yuanrong ZHU
1
;
Shu ZHANG
;
Jianmei ZHOU
;
Shenshen ZHANG
;
Lihong WU
;
Xiangpeng HU
Author Information
1. 安徽医科大学第二附属医院消化内科，合肥 230000
- Keywords:
Pancreatitis;
D-dimer;
Modified early warning score;
Severity;
Predictive ability
- From:
Chinese Journal of Primary Medicine and Pharmacy
2022;29(5):646-650
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the value of modified early warning score (MEWS) combined with D-dimer test in the establishment of an acute pancreatitis severity evaluation model.Methods:The clinical data of 357 patients with acute pancreatitis who received treatment in the Second Affiliated Hospital of Anhui Medical University, China between January 2017 and December 2018 were collected for this study. The receiver operating characteristic curve was used to determine the optimal cut-off value of MEWS combined with D-dimer test for predicting non-mild acute pancreatitis. The relationship between MEWS and D-dimer level was analyzed using regression analysis. The area under the curve (AUC) was used to evaluate the ability of each factor to predict the severity of acute pancreatitis. The sensitivity and specificity of the new model to predict non-mild acute pancreatitis were calculated.Results:According to the receiver operating characteristic curve, the AUC of D-dimer, MEWS, and new model were 0.702, 0.628 and 0.734 respectively ( P < 0.05). The AUC of the new model in predicting non-mild acute pancreatitis was significantly higher than that of MEWS and D-dimer test (0.734 > 0.702 > 0.628, Z = 3.20, P < 0.01). Conclusion:The ability of the new model established based on MEWS and D-dimer to predict the severity of acute pancreatitis is stronger than that of each of MEWS and D-dimer. The new model is simple, convenient and more suitable for clinical use.
