Influential factors of stereotactic radiotherapy for primary liver cancer
10.3760/cma.j.issn1008-6706.2022.02.027
- VernacularTitle:影响立体定向放射治疗原发性肝癌效果的相关因素分析
- Author:
Ruqin WANG
1
;
Zhendong GAO
;
Zongyi GAO
Author Information
1. 滨州市中心医院放疗科,滨州 251700
- Keywords:
Liver cancer,primary;
Stereotactic radiation;
Influencing factors;
Maximum diameter;
Portal vein tumor thrombus;
Psuedocapsule;
The Child - Pugh,classificat
- From:
Chinese Journal of Primary Medicine and Pharmacy
2022;29(2):285-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the factors affecting the therapeutic effects of stereotactic radiotherapy on primary liver cancer.Methods:The clinical data of 116 patients with primary liver cancer who received stereotactic radiotherapy in Binzhou Central Hospital from February 2018 to April 2020 were retrospectively analyzed. The factors that affect the therapeutic effects of stereotactic radiotherapy on primary liver cancer were analyzed.Results:Stereotactic radiotherapy was effective in 85 patients, with an overall response rate of 73.28%. There were no significant differences in maximum tumor diameter, arteriovenous fistula, portal vein tumor thrombus, distant metastasis, pseudocapsule, liver function Child-Pugh grade, Barcelona clinic liver cancer staging, and the number of stereotactic radiotherapies between different patients ( χ2 = 14.71, 12.76, 19.16, 8.54, 7.30, 7.71, 9.41, 4.08, P < 0.05 or < 0.01). Maximum tumor diameter, portal vein tumor thrombus, pseudocapsule, liver function Child-Pugh grade, Barcelona clinic liver cancer staging, and the number of stereotactic radiotherapies were the independent risk factors that affect the therapeutic effects of stereotactic radiotherapy on primary liver cancer (Wald χ2 = 3.13, 3.75, 4.16, 5.20, 3.90, 3.40, all P < 0.05). Conclusion:Many factors affect the therapeutic effects of stereotactic radiotherapy on primary liver cancer. Early identification of the high-risk factors for primary liver cancer is conducive to minimizing the risk of stereotactic radiotherapy, improving the therapeutic effects of stereotactic radiotherapy, and improving the prognosis. This study is highly innovative and scientific.
