Carbon dots derived from Poria cocos polysaccharide as an effective"on-off"fluorescence sensor for chromium(Ⅵ)detection
- Author:
Qianqian HUANG
1
;
Qianqian BAO
;
Chengyuan WU
;
Mengru HU
;
Yunna CHEN
;
Lei WANG
;
Weidong CHEN
Author Information
1. Anhui Province Key Laboratory of Chinese Medicinal Formula,Anhui University of Chinese Medicine,Hefei,230012,China
- Keywords:
Carbon dots;
Alkali-soluble Poria cocos polysaccharide;
Cr(Ⅵ)detection;
Internal filtering effect;
Static quenching effect
- From:
Journal of Pharmaceutical Analysis
2022;12(1):104-112
- CountryChina
- Language:Chinese
-
Abstract:
Chromium is a harmful contaminant showing mutagenicity and carcinogenicity.Therefore,detection of chromium requires the development of low-cost and high-sensitivity sensors.Herein,blue-fluorescent carbon quantum dots were synthesized by one-step hydrothermal method from alkali-soluble Poria cocos polysaccharide,which is green source,cheap and easy to obtain,and has no pharmacological ac-tivity due to low water solubility.These carbon quantum dots exhibit good fluorescence stability,water solubility,anti-interference and low cytotoxicity,and can be specifically combined with the detection of Cr(Ⅵ)to form a non-fluorescent complex that causes fluorescence quenching,so they can be used as a label-free nanosensor.High-sensitivity detection of Cr(Ⅵ)was achieved through internal filtering and static quenching effects.The fluorescence quenching degree of carbon dots fluorescent probe showed a good linear relationship with Cr(Ⅵ)concentration in the range of 1-100 μM.The linear equation was F0/F=0.9942+0.01472[Cr(Ⅵ)](R2=0.9922),and the detection limit can be as low as 0.25 μM(S/N=3),which has been successfully applied to Cr(Ⅵ)detection in actual water samples herein.
