The effects of breastfeeding within 2 weeks after birth on late-onset sepsis in very low birth weight infants
10.3760/cma.j.issn.2096-2932.2022.03.002
- VernacularTitle:生后2周内母乳喂养量对极低出生体重儿晚发型败血症的影响
- Author:
Huiyan WANG
1
;
Xiaoyun XIONG
;
Xueyu CHEN
;
Chuanzhong YANG
;
Lilian CHEN
;
Bingchun LIN
;
Chun CHEN
Author Information
1. 山西中医药大学护理学院，晋中 030600
- Keywords:
Infant,very low birth weight;
Infant,premature;
Late onset sepsis;
Breastfeeding
- From:Chinese Journal of Neonatology
2022;37(3):198-202
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of breastfeeding within 2 weeks after birth on late-onset sepsis in very low birth weight infants (VLBWI).Methods:From July 2018 to June 2019, clinical data of VLBWI (birth weight <1 500 g) born in our hospital were retrospectively reviewed. According to the proportion of breastfeeding volume in total feeding volume within 2 weeks after birth, the infants were assigned into high-proportion breastfeeding group (breastfeeding >50%), low-proportion breastfeeding group (breastfeeding ≤50%) and formula group. The incidences of late-onset sepsis among the three groups were compared using the chi-square test or Fisher's exact probability method. Logistic regression was used to analyze the effects of breastfeeding within 2 weeks after birth on late-onset sepsis.Results:The incidences of late sepsis in high-proportion breastfeeding group, low-proportion breastfeeding group and formula group were 0.4% (1/216), 8.1% (5/62) and 8.0% (2/25), respectively ( P<0.001). Logistic regression analysis showed that compared with the high-proportion breastfeeding group, the low-proportion breastfeeding group ( OR=17.844, 95% CI 2.005~158.775) and the formula group ( OR=23.261, 95% CI 1.916~282.350) had increased risks of late-onset sepsis. Conclusions:For VLBWI, high proportion breastfeeding (breastfeeding >50%) within 2 weeks after birth may reduce the risk of late-onset sepsis.
