Progress on the characteristics, prevention and treatment of neonatal central nervous system ureaplasma infection
10.3760/cma.j.issn.1673-4912.2022.05.013
- VernacularTitle:新生儿中枢神经系统脲原体感染的特点及其防治研究进展
- Author:
Lihua ZHANG
1
;
Meiyu ZHENG
;
Yue ZHANG
;
Xiaoming LYU
;
Hui WU
Author Information
1. 吉林大学白求恩第一医院新生儿科，长春 130012
- Keywords:
Neonates;
Ureaplasma;
Meningitis;
Central nervous system
- From:
Chinese Pediatric Emergency Medicine
2022;29(5):383-388
- CountryChina
- Language:Chinese
-
Abstract:
Ureaplasma is an opportunistic pathogen with a high population carrying rate.Maternal ureaplasma infection is related to adverse pregnancy outcomes such as premature birth etc.Ureaplasma infection in neonates can cause central nervous system inflammation and eventually lead to poor nervous system prognosis.Although the incidence of invasive central nervous system infection in newborns is low, due to the presence of immune escape in the body, atypical clinical manifestations after ureaplasma infection, and insensitivity to routine detection methods, the central ureaplasma infection in newborns is often unable to diagnose and treat properly in time, so it can easily lead to delayed treatment, which can lead to serious complications.This review aimed to explain the pathogenesis, clinical manifestations and complications of central nervous system inflammation caused by ureaplasma infection, and share diagnosis methods, as well as successful treatment experience in related cases, so as to provide the basis for early diagnosis and reasonable treatment, thereby reducing the occurrence of adverse neurological outcomes caused by ureaplasma infection.
