Discussion on the rationality of clinical application of prolonging antibiotic infusion time
10.3760/cma.j.issn.1673-4912.2022.05.004
- VernacularTitle:延长抗生素输注时间在临床应用的合理性探讨
- Author:
Jiayue XU
1
;
Xiaodong ZHU
Author Information
1. 上海交通大学医学院附属新华医院小儿急危重症医学科 200092
- Keywords:
Antimicrobial stewardship programs;
Prolonged infusion;
β-lactams;
Vancomycin;
Children
- From:
Chinese Pediatric Emergency Medicine
2022;29(5):335-340
- CountryChina
- Language:Chinese
-
Abstract:
The rapidly growing emergence of drug resistant bacteria has become one of the most important public health concerns.However, the development of new drugs is of more difficulties.Extended infusion or prolonged infusion of antibiotics is a significant way of antimicrobial stewardship programs, which has been proven beneficial to better pharmacokinetic/pharmacodynamic targets attainment and improved clinical outcomes.This review discussed the rationality of prolonging the infusion time of commonly used antibiotics in PICU.