The Effect of Whole Body Irradiation for the Treatment of Myasthenia Gravis.
- Author:
Young Bae LEE
1
;
Kyoung Hoon HONG
;
Myung Kwon KIM
;
Hee Tae KIM
;
Seung Hyun KIM
;
Ju Han KIM
;
Myung Ho KIM
Author Information
1. Department of Neurology, Hanyang university Hospital.
- Publication Type:Original Article
- MeSH:
Follow-Up Studies;
Humans;
Myasthenia Gravis*;
Whole-Body Irradiation*
- From:Journal of the Korean Neurological Association
1996;14(1):197-205
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study is designed to evaluate the effect of low-dose whole body irradiation (WBI) for treatment of myasthenia gravis(MG) and changes of immunological parameters. According to MG protocol of low dose WBI, eleven patients were selected and followed up for at least one year. Clinical status and immunological parameters were assessed at the time of pretreatment (baseline) and 1, 2, 3, 6, 12 months after initial dose irradiation. The improvement began five weeks after WBI and lasted for 12-month follow-up in 7 patients (good responders) Clinical improvement and immunological changes were more pronounced in good responders. So, it is suggested that low dose WBI may have the role in the treatment of the MG as an another therapeutic modality.
