A follow-up study on the prognosis of pediatric arterial ischemic stroke
10.3760/cma.j.issn.1673-4912.2021.12.001
- VernacularTitle:儿童动脉缺血性脑卒中的预后追踪研究
- Author:
Yilin PANG
1
;
Jie WU
;
Long WANG
;
Chengye ZHANG
;
Guangyuan ZHAO
;
Feng HUO
;
Quan WANG
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院急诊内科 100045
- Keywords:
Arterial ischemic stroke;
Cerebral infarction;
Children;
Prognosis;
Modified Rankin scale score
- From:
Chinese Pediatric Emergency Medicine
2021;28(12):1041-1046
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the prognosis of pediatric arterial ischemic stroke(PAIS).Methods:We retrospectively analyzed the clinical data of patients aging from 1 month to 18 years old who were diagnosed with PAIS at the Emergency Department of Beijing Children′s Hospital from July 2015 to April 2020.We used the modified Rankin scale(MRS)to evaluate patients.We analyzed their recovery of neurological function, mortality rates, and the recurrence of PAIS, while statistically calculating the risk factors leading to disability and death caused by PAIS.Results:A total of 101 children with PAIS were involved.During the follow-up period, 32.7%(33/101)had no obvious neurological sequelae(MRS 0), and 24.8%(25/101)had mild symptoms that did not affect the patients′daily life(MRS 1). The proportion of mild disability(MRS 2)and moderate to severe disability(MRS 3-5)were 13.9%(14/101)and 9.9%(10/101), respectively.Notably, 18.8%(19/101)of the patients died during the follow-up period, and PAIS-related fatality rate was 7.9%.Of the 49 patients with MRS score of 1-5, 89.8%(44/49)had dyskinesia, 16.3%(8/49)had language disorder, 10.2%(5/49)had epilepsy, 10.2%(5/49)had intellectual impairment, and 4.1%(2/49)had memory impairment.Four children relapsed during the follow-up period.Infantile onset, cardiogenic stroke, consciousness disorder and multiple angiopathy may be the risk factors of severe disability and death of PAIS.Conclusion:PAIS has a certain probability of mortality and disability.Infantile onset, complicated with consciousness disorder, cardiogenic stroke and multiple angiopathy are risk factors for poor prognosis.
