A retrospective study of high-flow nasal cannula oxygen therapy in patients with acute respiratory failure
10.3760/cma.j.cn211501-20210304-00642
- VernacularTitle:经鼻高流量湿化氧疗在急性呼吸衰竭患者中应用效果的回顾性研究
- Author:
Min GAO
1
;
Zeya SHI
;
Xiaotong HAN
;
Hui WEN
;
Maiying FAN
;
Xingwen ZHANG
;
Fengling NING
Author Information
1. 湖南省人民医院呼吸治疗专科，长沙 410005
- Keywords:
Humidified high-flow nasal cannula;
Acute respiratory failure;
Emergency department
- From:
Chinese Journal of Practical Nursing
2022;38(5):327-332
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect of high-flow nasal cannula (HFNC) oxygen therapy in patients with acute respiratory failure, and investigate the indicators that predict the failure of HFNC.Methods:The clinical data of 174 patients with acute respiratory failure were retrospectively analyzed. The patients were treated with HFNC in the Emergency Department of Hunan Provincial People′s Hospital from January 2018 to September 2020. The vital signs, blood gas analysis, Borg score and ROX index of patients before and one hour after HFNC application were compared, and the application effect of HFNC was judged. The HFNC failure group was defined as patients with respiratory support upgraded to non-invasive ventilation, endotracheal intubation or death within 48 h, and the indicators for predicting the HFNC failure were analyzed.Results:The failure rate of HFNC was 24.13%(42/174). There were significant differences in the heart rate, SpO 2, systolic blood pressure, diastolic blood pressure and PaO 2 of successfal group before and after the use of HFNC, t values were -8.12-4.60, all P<0.05. Multivariate Logistic regression analysis showed that the change value of systolic blood pressure was a protective factor of the failure of HFNC ( OR=0.967, 95% CI were 0.949-0.985, P<0.05). Conclusions:The application of HFNC in patients with acute respiratory failure is feasible and effective, and the change value of systolic blood pressure is an indicator to predict the failure of HFNC.
