Advances in applied research of Rivaroxaban in children with thromboembolic disease
10.3760/cma.j.cn101070-20201209-01874
- VernacularTitle:利伐沙班在儿童血栓栓塞性疾病的应用研究进展
- Author:
Yuzhuo SUN
1
;
Ping LUO
Author Information
1. 中南大学湘雅医院药学部，长沙 410008
- Keywords:
Rivaroxaban;
Direct oral anticoagulants;
Thrombosis;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(9):710-713
- CountryChina
- Language:Chinese
-
Abstract:
Rivaroxaban has been widely used for prevention and treatment of pulmonary embolism in adults due to the convenience of oral taking, rapid effect, less drug interaction, less influence by diet, no need of monitoring and fixed dose.However, its clinical application in children has been controversial.The EINSTEIN-Jr clinical trial and case reports at home and abroad have demonstrated the safety and effectiveness of Rivaroxaban in children with venous thrombus embolism.Therefore, Rivaroxaban can be considered as an alternative to standard anticoagulant therapy for children with venous thrombus embolism.This study reviews the application progress of Rivaroxaban in children with thromboembolic diseases.
