Research progress of the application of fecal microbiota transplantation in pediatric diseases
10.3760/cma.j.cn101070-20200824-01401
- VernacularTitle:粪菌移植在儿科应用的研究进展
- Author:
Yuanzhen ZHANG
1
;
Yugui ZENG
;
Xiaojing NIE
Author Information
1. 厦门大学附属东方医院儿科，福州 350025
- Keywords:
Child;
Fecal microbiota;
Transplantation;
Clostridium difficile;
Recurrent infection;
Inflammatory bowel disease;
Autism spectrum disorder
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(4):311-314
- CountryChina
- Language:Chinese
-
Abstract:
Fecal microbiota transplantation (FMT) has been reported to exert potential therapeutic value in gut microbiota dysbiosis.During FMT, the fecal material is transferred from a healthy donor into the gastrointestinal tract of a recipient via naso-gastric tube, enema, colonoscopy or oral capsules, aiming to reconstruct intestinal flora, ameliorate the dysbiotic state, control inflammation and modulate the immunity.FMT is recognized as a high-efficient and safe treatment option for recurrent clostridium difficile infection.It has been approved by the United States Food and Drug Administration for clinical use in the USA.FMT is a safe and effective treatment for patients with infla-mmatory bowel disease or autism spectrum disorder.
