Guidelines for diagnosis and nutritional intervention of mild to moderate non-IgE mediated cow′s milk protein allergy in Chinese infants
10.3760/cma.j.cn101070-20220106-00016
- VernacularTitle:中国婴儿轻中度非IgE介导的牛奶蛋白过敏诊断和营养干预指南
- Author:
Tongxin CHEN
1
;
Li HONG
;
Hua WANG
;
Jie SHAO
;
Fan YANG
;
Ying WANG
;
Guanghui LIU
;
Xiwei XU
;
Xiao-Yang SHENG
;
Chundi XU
Author Information
1. 国家儿童医学中心(上海),上海交通大学医学院附属上海儿童医学中心过敏/免疫科,上海 200127
- Keywords:
Cow′s milk protein allergy;
Guideline;
Non-IgE mediated;
Infant;
Diagnosis;
Nutritional intervention
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(4):241-250
- CountryChina
- Language:Chinese
-
Abstract:
Cow′s milk protein allergy (CMPA) is one of the most common presentations of food allergy seen in early childhood.It is an abnormal immune response caused by cow′s milk protein.CMPA can be clinically subdivided into either immediate-onset IgE mediated or delayed onset non-IgE mediated, or both.At present, concerns regarding the early and timely diagnosis of CMPA have been high-lighted over the years and there are many expert consensus on CMPA in China, but these consensus did not distinguish IgE mediated or non-IgE mediated CMPA.In view of the obvious clinical differences between the two type of CMPA and non-IgE mediated CMPA is more common in infancy, experts focus on pediatric gastroenterology, allergy/immunology, dermatology, nutrition and child healthcare convened by the Allergy Prevention and Control Professional Committee of Chinese Preventive Medicine Association present this guideline to help practitioners in primary care settings to early recognize and make suitable management of non-IgE mediated CMPA in China.The guideline incorporates the cutting-edge international guidance and the actual situation of Chinese children describing in detail the types, clinical features, diagnosis and nutritional intervention of non-IgE mediated CMPA.There are 42 recommendations in 7 categories in total referring to the common questions related to non-IgE mediated CMPA.