Case report of lung transplantation for cystic fibrosis in a child
10.3760/cma.j.cn101070-20210615-00687
- VernacularTitle:肺移植治疗儿童囊性纤维化1例
- Author:
Zizhu WANG
1
;
Hao WANG
;
Lanqin CHEN
;
Jianxin HE
;
Baoping XU
;
Kunling SHEN
Author Information
1. 国家儿童医学中心，国家呼吸系统疾病临床医学研究中心，首都医科大学附属北京儿童医院呼吸科，北京 100045
- Keywords:
Cystic fibrosis;
Lung transplantation;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(3):216-218
- CountryChina
- Language:Chinese
-
Abstract:
Objective:A case of cystic fibrosis admitted in the Respiratory Department of Beijing Children′s Hospital, Capital Medical University in June 2018 and underwent lung transplantation later was analyzed retrospectively.A 10-year-old girl had intermittent productive cough for more than 4 years with clubbed-finger.The lung high resolution CT (HRCT) showed bronchiectasis and mucus impaction, and the nasal sinus HRCT showed sinusitis.She had cystic fibrosis transmembrane conductance regulator ( CFTR) gene complex heterozygous mutation and positive sweat test.The immunoglobulin E (IgE) level and eosinophil count increased, and aspergillus fumigatus-specific IgE was positive.She was diagnosed as cystic fibrosis, allergic bronchopulmonary aspergillosis and sinusitis.Anti-infection, glucocorticoid and symptomatic treatment were given.During the following 21 months, the child had repeated respiratory difficulties and respiratory failure.Her lung function declined.Bilateral lung transplantation was performed in March 2020.She had a good recovery at more than 1 year and 3 months postoperatively.
