Advances in tissue engineering treatment of epiphyseal plate injury in children
10.3760/cma.j.cn101070-20200723-01238
- VernacularTitle:儿童骺板损伤组织工程学治疗研究进展
- Author:
Yiwei WANG
1
;
Ruiqi LI
;
Pengfei ZHENG
Author Information
1. 南京医科大学附属儿童医院骨科，南京 210000
- Keywords:
Child;
Epiphyseal plate injury;
Tissue engineering;
Regeneration
- From:
Chinese Journal of Applied Clinical Pediatrics
2022;37(2):153-157
- CountryChina
- Language:Chinese
-
Abstract:
Epiphyseal plate injury in children is very common, which can be caused by fracture, infection, malignant tumors, iatrogenic injury or other causes.Growth arrest and angulation or rotation deformity after epiphyseal plate injury would seriously affect the physical and mental health of children.At present, the success rate of bone bridge resection combined with corresponding material filling is super low.The construction of bioactive epiphyseal cartilage using cartilage tissue engineering technology has become a new research direction for the treatment of epiphyseal plate injury in children.Therefore, this review focuses on the current research on the regeneration of epiphyseal cartilage from the perspective of 3 elements of tissue engineering: seed cells, growth factors, and tissue engineering scaffolds.
