Research progress on host restriction factors of respiratory viruses
10.3760/cma.j.cn101070-20210728-00897
- VernacularTitle:呼吸道病毒感染中宿主限制因子研究进展
- Author:
Dandan LIN
1
;
Weijing YUAN
;
Linni ZHANG
;
Xiaobo LEI
;
Lili REN
;
Jianwei WANG
Author Information
1. 中国医学科学院&北京协和医学院病原生物学研究所，卫生部病原系统生物学重点实验室，北京 100730
- Keywords:
Influenza virus;
Enterovirus;
Rhinovirus;
Adenovirus;
Coronavirus;
Human orthopneumovirus;
Host restriction factor
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(24):1903-1906
- CountryChina
- Language:Chinese
-
Abstract:
Respiratory viruses can cause a variety of serious respiratory infections and diseases of tissues and organs outside the respiratory tract, raising a potentially severe threat to the society.Virus replication and survival rely on the internal mechanism of host cells, and the latter also produce a variety of restriction factors that target viral invasion, genome transcription and replication, and assembly and release to block viral infection.Herein, this study reviewed the research progress of the antiviral effects of the host restriction factors of common respiratory viruses and their underlying mechanisms.
