Viral infection and epidemiological characteristics of human metapneumovirus in febrile respiratory syndrome cases in nine provinces in China from 2009 to 2021
10.3760/cma.j.cn101070-20210908-01095
- VernacularTitle:2009年至2021年我国9省份发热呼吸道症候群病例中人偏肺病毒感染情况及流行特征分析
- Author:
Aili CUI
1
;
Zhibo XIE
;
Pengbo YU
;
Runan ZHU
;
Yingwei MA
;
Xingyu XIANG
;
Liping ZHANG
;
Yun ZHU
;
Julong WU
;
Zhenguo GAO
;
Rongbo ZHANG
;
Guangyue HAN
;
Wenbo XU
;
Yan ZHANG
Author Information
1. 国家卫生健康委员会医学病毒和病毒病重点实验室，世界卫生组织西太平洋地区麻疹/风疹参比实验室，中国疾病预防控制中心病毒病预防控制所麻疹室，北京 102206
- Keywords:
Febrile respiratory syndrome;
Human metapneumovirus infection;
Epidemic characteristics
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(24):1861-1865
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To clarify the infection and epidemic characteristics of the human metapneumovirus (HMPV) in Chinese patients with febrile respiratory syndrome (FRS), and to provide important baseline data for clinical diagnosis, treatment, prevention and control of HMPV-induced respiratory tract diseases in China.Methods:FRS cases from January 2009 to June 2021 in 9 provinces in China, including Beijing, Hebei, Jilin, Shandong, Shaanxi, Xinjiang, Anhui, Guangdong, Hunan were retrospectively analyzed for their respiratory samples, clinical and epidemic data.The respiratory samples were detected for HMPV by quantitative real-time PCR.Results:A total of 11 660 cases were tested for HMPV, involving 296 (2.54%) HMPV-positive cases.Among 296 HMPV-positive cases, 218 were single HMPV infection, and 78/296 (26.35%) were co-infected with one or more respiratory viruses.HMPV mainly affected children under 5 years of age (3.10%), and in this population, the proportion of pneumonia in HMPV co-infection cases was significantly higher than that of single HMPV infection.HMPV could be detected all year round, which was more popular in winter and spring, with the peak of HMPV epidemic in March.Conclusions:HMPV is one of the important pathogens causing acute respiratory infection in children, showing a clear seasonal epidemic.HMPV can be infected alone or in combination with other respiratory viruses, which may increase the risk of pneumonia in children.
