Analysis of risk factors of acute kidney injury in acute respiratory distress syndrome patients with mechanical ventilation
10.3760/cma.j.issn.1671-0282.2021.12.014
- VernacularTitle:有创通气的急性呼吸窘迫患者发生急性肾损伤的危险因素分析
- Author:
Xuehua PU
1
;
Mengnan TANG
;
Haitao HU
;
Fengfeng ZHU
;
Xia WANG
;
Tiantian ZHOU
;
Chongwen NIAN
;
Jilu YE
Author Information
1. 泰州市人民医院重症医学科，225300
- Keywords:
Mechanical ventilation;
Acute respiratory distress syndrome;
Acute kidney injury;
Risk factors
- From:
Chinese Journal of Emergency Medicine
2021;30(12):1489-1493
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors of acute kidney injury (AKI) in acute respiratory distress syndrome (ARDS) patients with mechanical ventilation.Methods:A retrospective analysis was conducted. ARDS patients with mechanical ventilation admitted to ICU of Taizhou People's Hospital from January 2019 to December 2019 were enrolled. Patients were divided into the AKI group and non-AKI group according to whether the patients had AKI. Clinical characteristics and laboratory indicators of the two groups were compared. Risk factors of incidence of AKI in ARDS patients were analyzed. The Kaplan-Meier survival curve was drawn to evaluate the survival rates of the two groups.Results:A total of 120 ARDS patients with mechanical ventilation were included, and 57 patients (47.5%) developed AKI. Procalcitonin, increased basal creatinine, decreased pH and impaired consciousness were independent risk factors for AKI in ARDS patients with mechanical ventilation. Fifty-seven of the 120 patients died with a mortality of 38.3%. The Kaplan-Meier survival curve showed that the survival rate of the AKI group was significantly lower than that of the non-AKI group ( P<0.001). Conclusions:The incidence and mortality of AKI is high in ARDS patients with mechanical ventilation. Procalcitonin, increased basal creatinine, decreased pH and impaired consciousness are independent risk factors for AKI in ARDS patients with mechanical ventilation.
