Research progress on the mechanism of tonifying kidney and activating blood Chinese medicine for knee osteoarthritis
10.3760/cma.j.cn115398-20210509-00069
- VernacularTitle:补肾活血中药治疗膝骨关节炎作用机制研究进展
- Author:
Yuandong LI
1
;
Ping WANG
;
Juntao ZHANG
;
Chao ZHANG
;
Hanmei BU
;
Aifeng LIU
Author Information
1. 天津中医药大学第一附属医院骨伤科 国家中医针灸临床医学研究中心，天津 300381
- Keywords:
Osteoarthritis, knee;
Tonifying kidney and activating blood;
Traditional Chinese Medicine;
Mechanism of action;
Review
- From:
International Journal of Traditional Chinese Medicine
2022;44(5):595-598
- CountryChina
- Language:Chinese
-
Abstract:
The important pathogenesis of knee osteoarthritis (KOA) lies in kidney deficiency and blood stasis. Therefore, Traditional Chinese Medicine (TCM) for tonifying the kidney and activating blood circulation is widely used in clinical practise with high response. The existing literature mainly focuses on single medicine for tonifying the kidney and activating blood circulation, as well as TCM compounds, such as classic prescriptions Yougui Pill, Duhuo Jisheng Decoction, which contain TCMs for tonifying the kidney and activating blood circulation, or self-made empirical prescriptions Bushen Huoxue Recipe and Bushen Tongluo Recipe, which are based on the idea of tonifying the kidney and activating blood circulation. The above TCMs mainly regulate oxidative stress response, inflammatory cytokine level, no level, lymphatic function and microcirculation Inhibit chondrocyte apoptosis, regulate cartilage metabolism, protect and repair cartilage, and inhibit matrix degrading enzymes to play a therapeutic role.
