Research on the rule of ancient prescriptions of yin deficiency syndrome
10.3760/cma.j.cn115398-20210527-00267
- VernacularTitle:阴虚证古方用药规律研究
- Author:
Ziling ZENG
1
;
Lin TONG
;
Sihong LIU
;
Fen JIANG
;
Huamin ZHANG
Author Information
1. 中国中医科学院中医药信息研究所古籍资源研究室，北京 100700
- Keywords:
Yin deficiency;
Chinese medicine formula;
Data mining;
Medication rules;
Core drug;
the Ancient and Modern Medical Case Cloud Platform
- From:
International Journal of Traditional Chinese Medicine
2022;44(1):67-72
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The data mining method was used to analyze the medication rules of the ancient prescriptions for yin deficiency syndrome, so as to provide reference for clinical treatment of yin deficiency syndrome.Methods:We searched the database of ancient prescriptions, selected the prescriptions for yin deficiency syndrome, used the Ancient and Modern Medical Case Cloud Platform V2.2.3 to count the frequency and attribute of drug use, and carried out hierarchical cluster analysis to find the core prescription. MATLAB was used to analyze the association rules, and the law of drug compatibility was found. The Pajek64 5.13 was used for complex network analysis to find out the core traditional Chinese medicine.Results:There were 467 prescriptions that meet the requirements, 302 kinds of drugs were used in total. The four properties of the drugs were mainly cold, the five flavors mainly sweet, the meridian of the drugs mainly kidney meridian. The core drugs were Rehmanniae Radix Praeparata, Ophiopogonis Radix, Rehmanniae Radix, and Poria. The most commonly used drug pair was Dioscoreae Rhizoma- Rehmanniae Radix Praeparata, the second was Corni Fructus- Rehmanniae Radix Praeparata, Poria-Rehmanniae Radix Praeparata. The commonly used drugs can be clustered into two categories. Conclusion:We can preliminarily reveal that the ancient medication law of yin deficiency syndrome is mainly nourishing Yin liquid and reducing fire, paying attention to nourishing kidney yin, using Yin nourishing medicine often combined with medicine of tonifying lung, liver, spleen yin and diverging to reduce fever. It can provide certain reference for clinical treatment of yin deficiency syndrome.
