Research progress on anti-tumor mechanism of Tubeimoside-1
10.3760/cma.j.cn115398-20200913-00123
- VernacularTitle:土贝母苷甲抗肿瘤机制研究进展
- Author:
Liu SUN
1
;
Xueyuan MIAO
;
Qing PENG
;
Lina LIU
;
Qinghuai ZHANG
;
Chunze ZHANG
Author Information
1. 天津中医药大学2018级硕士研究生，天津 301617
- Keywords:
Bolbostemmatis Rhizoma;
Tubeimoside-1;
Tumor;
Antineoplastic drugs, phytogenic;
Mechanism of action;
Review
- From:
International Journal of Traditional Chinese Medicine
2022;44(1):110-113
- CountryChina
- Language:Chinese
-
Abstract:
Tubeimoside-1 (TBMS1) is a triterpene saponins active components with large content in Cucurbitaceae plant Fritillaria, which is water-soluble and stable. It has a broad inhibitory effect on lung cancer, colorectal cancer, breast cancer, gastric cancer and other tumors. The mechanism is mainly related to the inhibition of tumor cell growth, induction of tumor cell apoptosis, inhibition of tumor cell invasion and metastasis, induction of cell autophagy, and inhibition of tumor angiogenesis.
