Treatment with Low-Dose Danazol in Livedo Vasculitis.
- Author:
Seung Hyun MOON
;
Kwang HYUN
- Publication Type:Original Article
- Keywords:
Livedo vasculitis;
Danazol
- MeSH:
Danazol*;
Humans;
Ulcer;
Vasculitis*
- From:Korean Journal of Dermatology
1999;37(2):163-167
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Several modalities have been used for the treatment of livedo vasculitis. However, in some cases conspicious morbidity is caused by recurrent painful ulceration resistant to therapy. OBJECTIVE: This study was conducted to determine the effectiveness and adverse effects of the danazol in treatment of livedo vasculitis. METHODS: Nine patients with ulcerative lesions due to livedo vasculitis were included for danazol therapy. Danazol 200mg was administered daily for 4 to 8 weeks. RESULTS: Eight of the patients showed remarkable improvement and were satisfied with this therapy. Significant adverse effects were not observed. CONCLUSION: We suggest that a low dose of danazol may be considered as the first line of treatment and is worthwhile to try in cases recalcitrant to the other treatment.