Research progress on lncRNAs as members of ceRNA network in melanoma
10.3760/cma.j.cn371439-20210520-00009
- VernacularTitle:长非编码RNA作为竞争性内源RNA在黑色素瘤中的研究进展
- Author:
Anlan HONG
1
;
Meng CAO
;
Yan WANG
;
Fang FANG
Author Information
1. 中国医学科学院北京协和医学院皮肤病医院皮肤外科，南京 210042
- Keywords:
Melanoma;
RNA, long noncoding;
MicroRNAs;
Competing endogenous RNA
- From:
Journal of International Oncology
2022;49(1):61-64
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, there has been an increasing number of studies on long non-coding RNAs (lncRNAs) as a competing endogenous RNA (ceRNA) in melanoma. Different lncRNAs show high or low expression in melanoma, and competitively combine with miRNAs through ceRNA mechanism, affecting the expression of downstream target mRNAs, thereby playing the role of oncogenes or tumor suppressor genes. Understanding the role of lncRNA as ceRNA in melanoma can provide new ideas for the diagnosis and treatment of melanoma in the future.
