A Case of Woringer Kolopp Disease Treated with Topical PUVA.
- Author:
Jae Bong LEE
;
Ho Sun JANG
;
Chang Keun OH
;
Kyung Sool KWON
;
Tae Ahn CHUNG
- Publication Type:Case Report
- Keywords:
Woringer Kolopp disease;
Topical PUVA
- MeSH:
Adult;
Biopsy;
Blood Cell Count;
Dermis;
Eczema;
Epidermis;
Humans;
Leukocytes;
Liver;
Pagetoid Reticulosis*;
Thigh;
Urinalysis
- From:Korean Journal of Dermatology
1999;37(2):239-243
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 26-year-old Korean man had an erythematous scaly plaque on his right thigh for fifteen years. He was diagnosed with chronic eczema and treated with topical steroid, but no clinical improvement was obtained for 15 years. Laboratory studies including complete blood cell count, urinalysis, liver and renal function test, and peripheral blood smear were normal. A biopsy specimen showed hyperkeratosis, acanthosis, and mononuclear cellular infiltration in the epidermis. These cells had a perinuclear halo and showed a Pautrier's microabscess like configuration. In the dermis, there was a band like infiltration of inflammatory cells. Infiltrates of the epidermis were negative for leukocyte common antigen(CD45) and positive for Pan T cell(CD45RO). He was treated with topical PUVA twice a week for twelve weeks. Clinical and pathological improvements were obtained. We propose PUVA may be a useful therapeutic modality to treat Woringer Kolopp disease.
