Antiplatelet therapy of patients with intracranial aneurysms undergoing stent-assisted coil embolization
10.3760/cma.j.issn.1673-4165.2022.03.012
- VernacularTitle:颅内动脉瘤支架辅助弹簧圈栓塞患者的抗血小板治疗
- Author:
Hongfu DU
1
;
Yichen LI
;
Manman XU
;
Tao LIU
;
Manman YI
;
Weihong GE
;
Feng YU
Author Information
1. 中国药科大学南京鼓楼医院，南京 210008
- Keywords:
Intracranial aneurysm;
Embolization, therapeutic;
Stents;
Platelet aggregation inhibitors;
Postoperative complications
- From:
International Journal of Cerebrovascular Diseases
2022;30(3):221-226
- CountryChina
- Language:Chinese
-
Abstract:
Stent-assisted coil embolization is a common endovascular treatment for ruptured/unruptured intracranial aneurysms. Stent implantation process can damage vascular endothelium, activate platelet and coagulation cascade, and then increase the risk of thrombosis. In order to reduce the risk of postoperative embolism, antiplatelet therapy is required. Among them, aspirin combined with clopidogrel dual antiplatelet therapy is a commonly used strategy. For patients with low response to clopidogrel, tigrelol or cilostazol can be used as an alternative drug. Although the scheme has been considered to be effective and safe, it is still controversial.
