Obesity paradox of ischemic stroke
10.3760/cma.j.issn.1673-4165.2022.02.009
- VernacularTitle:缺血性卒中的肥胖悖论
- Author:
Cuili TIAN
1
;
Lina SHI
;
Jia WANG
Author Information
1. 河北省第八人民医院康复科,石家庄 050011
- Keywords:
Stroke;
Brain ischemia;
Obesity;
Body mass index;
Treatment outcome
- From:
International Journal of Cerebrovascular Diseases
2022;30(2):124-128
- CountryChina
- Language:Chinese
-
Abstract:
Obesity is a recognized risk factor for stroke. However, many studies have shown that compared with normal weight and underweight patients, obese or overweight patients with ischemic stroke have lower risk of death and better functional outcome, suggesting that there is an obesity paradox in patients with ischemic stroke. In contrast, the obesity paradox was not observed in patients receiving reperfusion therapy, including intravenous thrombolysis and endovascular therapy. Therefore, whether there is obesity paradox in ischemic stroke is still controversial. Further high-quality evidence is needed to clarify the correlation between body weight and the outcome of ischemic stroke.