Role of microglia phagocytosis in acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2021.11.008
- VernacularTitle:小胶质细胞吞噬在急性缺血性卒中中的作用
- Author:
Xuemei CHEN
1
Author Information
1. 南京医科大学附属江宁医院神经内科 211100
- Keywords:
Stroke;
Brain ischemia;
Microglia;
Phagocytosis;
Inflammation
- From:
International Journal of Cerebrovascular Diseases
2021;29(11):845-849
- CountryChina
- Language:Chinese
-
Abstract:
Microglia, as an inherent immune cell in the brain, is an important defense line against central nervous system injury and participates in the pathogenesis of ischemic stroke. Especially the phagocytosis of microglia plays an important role in the pathogenesis of ischemic stroke. This article reviews the important role and phagocytic mechanism of microglia in acute ischemic stroke, and focuses on the dual effects of its phagocytic function on nerve injury and recovery after stroke, hoping to provide new targets and strategies for microglia-targeted acute ischemic stroke treatment.
