Similarities and differences in the pathogenesis of Henoch-Sch?nlein nephritis and IgA nephropathy
10.3760/cma.j.issn.1673-4408.2022.04.004
- VernacularTitle:紫癜性肾炎与IgA肾病发病机制的异同
- Author:
Jingqi LIU
1
;
Xiaochuan WU
Author Information
1. 中南大学湘雅二医院儿童医学中心，长沙 410011
- Keywords:
IgA nephropathy;
Henoch-Sch?nlein purpura nephritis;
Pathogenesis;
IgA1
- From:
International Journal of Pediatrics
2022;49(4):231-235
- CountryChina
- Language:Chinese
-
Abstract:
IgA vasculitis is a common autoimmune disease mediated by IgA in childhood, which can involve many systems.Henoch-Sch?nlein purpura nephritis(HSPN)is one of the main complications.Both HSPN and IgA nephropathy(IgAN)are common glomerulonephritis in children, but the former is the most common secondary glomerulonephritis and the latter is one of the most persistent diseases in primary glomerulonephritis.There are differences in clinical phenotype and prognosis.This article reviews the relevant literature, and summarizes the similarities and differences in the pathogenesis of HSPN and IgAN, so as to better understand the two diseases.
