Advance in prognostic factors of Graves disease in children
10.3760/cma.j.issn.1673-4408.2022.02.012
- VernacularTitle:儿童Graves病预后影响因素的研究进展
- Author:
Dandan CHEN
1
;
Qiaoli ZHOU
;
Wei GU
Author Information
1. 南京医科大学附属儿童医院内分泌科 210008
- Keywords:
Graves disease;
Children;
Antithyroid drugs treatment;
Prognosis;
Related factors
- From:
International Journal of Pediatrics
2022;49(2):123-126
- CountryChina
- Language:Chinese
-
Abstract:
Graves disease(GD) is the most common cause of hyperthyroidism in children.GD is an autoimmune thyroid disease which is based on genetic susceptibility and exacerbated by environmental factors including infection, toxin, drugs and stress.Antithyroid drugs(ATD) are the first-line treatment for GD in children.However, many children relapsed after discontinuing ATD, and the relapse rate between different children varied.Till now, exact cause has not been clarified.Previous studies prove that sex, age, micro-element, goiter size, thyroid hormone level, TRAb level, duration of ATD treatment and genetics may affect prognosis of pediatric GD.Yet predictors precious studies identified were variable.
