The origin and classification of cortical projection neuron
10.3760/cma.j.issn.1673-4408.2022.01.003
- VernacularTitle:大脑皮层投射神经元的起源与分型
- Author:
Yuting MEI
1
;
Yan CHENG
;
Xiaoli JI
;
Man XIONG
Author Information
1. 复旦大学附属儿科医院干细胞中心，上海 201102
- Keywords:
Cortical development;
Projection neurons;
Origin;
Classification;
Function
- From:
International Journal of Pediatrics
2022;49(1):10-14
- CountryChina
- Language:Chinese
-
Abstract:
As the main cell type in mammalian cortex, cortical projection neurons play an important role in brain functions, including motor control, sensation and cognition.Projection neurons in the cerebral cortex include excitatory projection neurons and inhibitory projection neurons, of which excitatory projection neurons are the main type.Cortical excitatory projection neurons have various subtypes, and most of them have their own unique developmental rules and molecular markers.Studying the origin and classification of projection neurons in the cerebral cortex is helpful to understand the mechanisms of diseases related to abnormal projection neurons.This paper reviews the origin, classification and function of cortical projection neurons.
