EB virus-positive discordant lymphoma: report of 1 case and review of literature
10.3760/cma.j.cn115356-20210725-00164
- VernacularTitle:EB病毒阳性不一致性淋巴瘤1例并文献复习
- Author:
Yi ZHAO
1
;
Yuan XIA
;
Xiaoxu ZHANG
;
Mengying YU
;
Jianfeng ZHU
Author Information
1. 南通大学附属泰州市人民医院血液科，泰州 225300
- Keywords:
Immunoblastic lymphadenopathy;
Lymphoma, T-cell;
Lymphoma, large B-cell, diffuse;
Discordant lymphoma
- From:
Journal of Leukemia & Lymphoma
2022;31(3):170-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical manifestations, laboratory tests, diagnosis and treatment of discordant lymphoma (DL).Methods:The clinical data of a patient with EB virus-positive DL admitted to Taizhou People's Hospital in November 2019 were retrospectively analyzed and the related literature was reviewed.Results:The patient underwent a cervical lymph node biopsy pathology examination at onset, and then results suggested angioimmunoblastic T-cell lymphoma (AITL). The patient subsequently developed gastrointestinal bleeding and underwent resection of small bowel lesions, and postoperative pathology suggested diffuse large B-cell lymphoma (DLBCL). The patient was finally diagnosed as DL. The R2-CHOP chemotherapy regimen was given to the patient, but the patient still had recurrent gastrointestinal bleeding and poor general condition. The patient refused chemotherapy and was changed to lenalidomide monotherapy. Finally, the patient died due to multiorgan failure, with an overall survival of 13 months.Conclusions:DL is rarely seen in lymphoma, whereas the combination of AITL and DLBCL is extremely rare. The clinicians need to improve the understanding of this disease to avoid misdiagnosis and missed diagnosis.
