Adrenal intravascular large B-cell lymphoma: report of 1 case and review of literature

VernacularTitle:肾上腺血管内大B细胞淋巴瘤1例并文献复习
Author: Biqi CHEN ¹ ; Baoan CHEN ; Zheng GE ; Wenduo HE ; Ping LI ; Jian CHENG
Author Information

1. 东南大学医学院，南京　210003
Keywords: Intravascular large B-cell lymphoma; Adrenal gland neoplasms; Lymphoma, B-cell; Diagnosis; Treatment
From: Journal of Leukemia & Lymphoma 2022;31(3):161-164
CountryChina
Language:Chinese
Abstract: Objective:To investigate the diagnosis and treatment of intravascular large B-cell lymphoma (IVLBCL).Methods:The clinical data of 1 patient with adrenal IVLBCL in Zhongda Hospital Southeast University in May 2020 were retrospectively analyzed, and the relevant literature was reviewed.Results:The patient was an elderly male with recurrent fever of unknown cause at initial stage, and was finally diagnosed as adrenal IVLBCL based on the results of laboratory, imaging and adrenal biopsy at different stages. After multiple courses of R-COP in combination with Bruton tyrosine kinase (BTK) inhibitor, the patient achieved complete remission.Conclusions:IVLBCL is rare and it lacks specific clinical symptoms. PET-CT and pathological biopsy can help in the diagnosis of it. R-COP combined with BTK inhibitor is effective in the treatment of biphenotype IVLBCL.